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A UPS car­go plane crashed and ex­plod­ed in a mas­sive fire­ball Tues­day while tak­ing off from the com­pa­ny’s glob­al avi­a­tion hub in Louisville, Ken­tucky, killing at least sev­en peo­ple and in­jur­ing 11, au­thor­i­ties said.

The Fed­er­al Avi­a­tion Ad­min­is­tra­tion said the plane crashed about 5:15 p.m. as it was de­part­ing for Hon­olu­lu from Louisville’s Muham­mad Ali In­ter­na­tion­al Air­port.

The plane crashed about 5:15 p.m. as it was de­part­ing for Hon­olu­lu from UPS World­port at Louisville Muham­mad Ali In­ter­na­tion­al Air­port.