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The Pan Amer­i­can Health Or­ga­ni­za­tion (PA­HO) has is­sued a new Rapid Risk As­sess­ment (RRA) on yel­low fever in the Amer­i­c­as—in­clud­ing the Caribbean—which it said shows that the risk to pub­lic health re­mains high due to con­tin­ued hu­man cas­es in en­dem­ic coun­tries of the re­gion.

PA­HO said that so far this year, there has been a more than 8-fold in­crease in cas­es com­pared to the same pe­ri­od of 2024.

It said this is due to the pe­ri­od­ic re­ac­ti­va­tion of syl­vat­ic trans­mis­sion cy­cles with spillover cas­es among peo­ple and that in to­tal, coun­tries have re­port­ed 221 con­firmed hu­man cas­es of yel­low fever, in­clud­ing 89 deaths.