(AP) — Efforts to unseat British Prime Minister Keir Starmer broke out into open rebellion Thursday, with one potential rival resigning from the Cabinet and another clearing the way for her to enter any future leadership contest.

Health Secretary Wes Streeting became the first senior minister to quit Starmer ’s Cabinet on Thursday in what is expected to be a precursor to challenging his leadership.

Starmer is facing growing pressure to step down after his Labour Party’s disastrous results last week in local and regional elections.